Clinical Investigation

The Efects of Ketamine Administration Before Spinal Anesthesia on Postoperative Analgesia In Elderly Patients Undergoing Hip Surgery

  • Selda SEN
  • Kutlay AYDIN

Meandros Med Dent J 2006;7(3):25-29

Aim and objective: Hip fracture represents the most leading cause of orthopedics urgent casesfor elderly people. Although spinal or epidural anesthesia is preferred in those cases, the pain due to position can cause some difficulty. The aim of our study is to investigate the analgesic effect of ketamine, fentanyl, or meperidine administration when given to facilitate the position before spinal anesthesia on postoperative analgesia in elderly patients underwent hip surgery. Material Methods: Eighty-nine elderly patients who underwent hip surgery by spinal anesthesia were investigated between August 2000 and October 2001 retrospectively. The patients were divided into four groups according to the application of analgesics before spinal anesthesia: Group 1 (Ketamine group), Group 2 (Fentanyl group), Group 3 (Meperidine group) and Group 4 (Control group). The time of first analgesic request for postoperative period and total analgesic consumption at postoperative 24 hour were recorded in all patients. Results: The age range of patients was between 65 and 99. The time to first request for analgesia was significantly longer in the ketamine (192 min) group compared to the fentanyl (132 min), meperidine (129 min) and control groups (118 min) (p=0.035). The analgesic requirements first 24 h were significantly lower in ketamine group compared to other groups (p0.001). Conclusions: Intravenously administration of ketamine before spinal anesthesia may provide better analgesia compared to other opioids during postoperative period in elderly underwent hip surgery.

Keywords: elderly, spinal anesthesia, analgesia, ketamine, fentanly, meperidine