Clinical Investigation

Outcome of Very low BirthWeight Infants Followed in the Neonatal Intensive Care Unit of Adnan Menderes University Faculty of Medicine

  • Münevver TÜRKMEN
  • Çaglar ACAR
  • Ayse TOSUN
  • Ayvaz AYDOGDU

Meandros Med Dent J 2006;7(3):3-6

Purpose: The aim of the study was to determine the mortality and morbidity rates for infants weighing 1500 g or less who were admitted to the neonatal intensive care unit of our hospital between 2000 and 2005.  Material and Methods: The charts of 61 low-birth-weight infants were evaluated retrospectively. The data consisted of patient information including socio-demographic characteristics, perinatal events, procedures such as surfactant replacement therapy, respiratory support and selected patient outcomes such as sepsis, intracranial hemorrhage, necrotizing enterocolitis, retinopathy of prematurity, chronic lung disease, mortality and morbidity rates and hospitalization times. Descriptive and frequency statistics, student-t test, Pearson correlation tests were used for statistical analysis. Results: Of 61 infants, 62% were male, 3% had ambiguous genitalia. The mean gestational age and birth weight were 29.0±2.2 (25-35) weeks and 1187±243 (580-1500) g,respectively. Fortysix and a half % of the cases had been delivered in our hospital and37%had premature and prolonged membrane rupture. The surfactant therapy rate was 20.8% and 70% of the cases had mechanical ventilation support. The median ventilation duration was 66 hours (0-960). The incidence of chronic lung disease was 26.4%. The incidence of sepsis diagnosed by blood culture was 31.8%. The survival rate was 82%. Conclusion: Our mortality rate was higher than developed countries but comparable to the rates of our country. Lower surfactant therapy rates compared with that of developed countries could lead to higher mechanical ventilation time and a higher incidence of chronic lung disease.

Keywords: Very low birth weight, outcomes, morbidity, mortality