Case Report

Inflammatory Pseudotumor of Lymph Nodes (A Case Report)

  • Füruzan KACAR
  • Ibrahim METEOGLU
  • Edi LEVI
  • Emel DIKICIOGLU
  • Gülten INAN

Received Date: 28.03.2001 Accepted Date: 29.06.2001 Meandros Med Dent J 2002;3(1):33-36

A 7 year-old boy presented with cervical lymph node enlargement, fever and elevated erythrocyte sedimentation rate. A neck mass measuring 3x2.5x1.5 cms was surgically removed. Histologically, the process showed a proliferation of spindle cells, associated with a mixture of inflammatory cells and small blood vessels involving the connective tissue framework (hilum, trabecula, capsule) of the lymph node. Immunohistochemical analysis showed spindle cells positive for muscle-spesific actin and vimentin, but negative for desmin. Histochemical, Ziehl-Neelsen stain was negative. With these clinical and histopathologic findings a diagnosis of “ inflammatory pseudotumor of lymph nodes” was made. Inflammatory pseudotumor of the lymph nodes is a rare, recently described benign cause of lymphadenopathy. The differential diagnosis includes other reactive processes, Castleman's dissease, malignant lymphoma (Hodgkin's lymphoma, peripheral T cell lymphoma) and malignant fibrous histiocytoma. This case is presented due to its rare occurrence along with areview of literature.

Keywords: Inflammatory pseudotumor, lymph node